Scientific Program (Hybrid Format)
Melioidosis and Glanders
Monday, May 16th, 2022
2:00-6:00 pm
Registration open
3:00-5:00 pm
International Melioidosis Committee closed meeting
6:00 pm
Welcome reception
Tuesday, May 17th, 2022
7:30 am
Registration open
8:30-8:45 am
Opening
8:45-10:15 am
CLINICAL ASPECTS & EPIDEMIOLOGY I
Invited Speakers
8:45 am
Bart Currie, Menzies School of Health Research, Darwin, Australia
Melioidosis: priority known unknowns
9:00 am
Alf Fuessel, European Commission, Health and Consumer Protection Directorate-General, Unit 2-Animal Health and Welfare, Brussels, Belgium
Global epidemiology of glanders
9:30 am
Emma Birnie, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands
Drivers of melioidosis endemicity: epidemiological transition, zoonosis, and climate change
Selected Presentations
10:00 am
Srujana Mohanty, All India Institute of Medical Sciences, Bhubaneswar, India
Musculoskeletal melioidosis: a single-centre experience from India over a 5-year period
10:15–10:45 am
Break
10:45–12:30 am
DIAGNOSTICS, ANTIBIOTICS & TREATMENT I
Invited Speakers
10:45 am
Karine Laroucau, ANSES Maisons-Alfort, Paris-Est University, Paris, France
Diagnostic challenges in glanders
11:15 am
Narisara Chantratita, Mahidol University, Bangkok, Thailand
Identification of biomarkers for predicting mortality in melioidosis
Selected Presentations
11:45 am
Mindy Elrod, Centers for Disease Control and Prevention, Atlanta, USA
12:00 am
Nguyen-Ho Lam, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Vietnam
Antimicrobial resistance of Burkholderia pseudomallei causing community-acquired pneumonia
12:15 pm
Kay Barnes, The Defence Science and Technology Laboratory, Salisbury, United Kingdom
Combination antibiotic therapy in a mouse model of inhalational melioidosis
12:30–1:30 pm
Lunch
1:30–3:00 pm
CLINICAL ASPECTS & EPIDEMIOLOGY II
Invited Speakers
1:30 pm
Jay Gee, Centers for Disease Control and Prevention, Atlanta, USA
Review of genomic analysis of Burkholderia pseudomallei associated with imports to the continental United States
2:00 pm
Jelmer Savelkoel, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands
A call to action: time to recognise melioidosis as a neglected tropical disease
2:30 pm
Anthony Solomon, World Health Organization, Geneva, Switzerland
Neglected tropical diseases at WHO, and the global NTD road map 2021–2030
3:00–3:30 pm
Break
3:30–4:30 pm
Flash talks 1 (2 slide)
Poster presentation 1
Mégane Gasqué Anticipating emergences: spatial and molecular epidemiology of Melioidosis in French overseas departments and territories.
Sergei Biryukov Cytokine Profiles of Subunit Hcp1-based and Live Attenuated Bp 668 ΔilvI Candidate Vaccines
Sophie Guillier Characterisation of the genetic evolution of Burkholderia thailandensis upon antibiotic stress
Fabienne Neulat-Ripoll RNAseq analysis on B. pseudomallei clinical isolates and impact of phenothiazines on resistance’s mechanisms
Sabine Lichtenegger B. pseudomallei core genome MLST analysis links melioidosis cases to a predominant genotype in a geographical B. pseudomallei hotspot
Sunee Chayangsu Clinical Prediction Rules for In-hospital Mortality Outcome in Melioidosis Patients
Bijayini Behera Evaluation of In Vitro Activity of Cefiderocol against Burkholderia pseudomallei by Broth Microdilution and Disk Diffusion
4:30–6:00 pm
DIAGNOSTICS, ANTIBIOTICS & TREATMENT II
Invited Speakers
4:30 pm
Herbert Schweizer, Northern Arizona University, Flagstaff, USA
Novel insights into antibiotic resistance of Burkholderia pseudomallei Complex Species
5:00 pm
Gabriel E. Wagner, Medical University of Graz, Graz, Austria
Point of care tests for melioidosis and glanders
Selected Presentations
5:30 pm
Adam Taylor, The Defence Science and Technology Laboratory, Salisbury & London School of Hygiene and Tropical Medicine, London, United Kingdom
Antibody-antibiotic conjugate for melioidosis
5:45 pm
Riccardo D’Elia, The Defence Science and Technology Laboratory, Salisbury, United Kingdom
7:30 pm
Conference Dinner
Wednesday, May 18th, 2022
7:30-8:30 am
Registration open
8:30–9:45 am
PATHOGENESIS & IMMUNE RESPONSE
Invited Speakers
8:30 am
Joanne Stevens, University of Edinburgh, Edinburgh, United Kingdom
Studies on the actin-based motility and its role in the intracellular survival of Burkholderia pseudomallei
9:00 am
Josh Hanson, Kirby Institute, Sydney, Australia
Melioidosis of the central nervous system; impact of the bimABm allele on patient presentation and outcome
Selected Presentations
9:30 am
Patpong Rongkard, University of Oxford, United Kingdom
T-cell dysregulation is associated with fatality in community-acquired melioidosis
9:45–10:15 am
Break
10:15–11:45 am
GENOMICS & ENVIRONMENTAL ASPECTS
Invited Speakers
10:15 am
Claire Chewapreecha, Mahidol University, Bangkok, Thailand
Genome-wide association study identifies bacterial factors associated with 28-day mortality in melioidosis patients
10:45 am
Rita Oladele, Lagos University Teaching Hospital, Lagos, Nigeria.
Selected Presentations
11:15 am
Karoline Assig, Medical University of Graz, Graz, Austria
Environmental factors associated with soil prevalence of the melioidosis pathogen Burkholderia pseudomallei: A longitudinal seasonal study from South West India
11:30 am
Apichai Tuanyok, University of Florida, Gainesville, FL, USA
A Comprehensive Study of Prophage Islands in Burkholderia pseudomallei Complex (BPC)
11:45–12:45 pm
Lunch
12:45-1:45 pm
Flash talks 2 (2 slides)
Poster presentation 2
Hoi Cheung The role of Type VI secretion systems in infection and competition of Burkholderia thailandensis
Miro Plum Type VI secretion system-5 of Burkholderia thailandensis assembles to lyse host cell protrusions
Megan Grund Bucl8-derived intranasal vaccine elicits distinct immune responses in an outbred murine model of melioidosis
Sarah Harding Modelling relapse of disease in a mouse model of melioidosis
Yuli Talyansky Host Background and Bacterial Isolate Determine Virulence and Inflammatory Response in a Burkholderia pseudomallei Mouse Model
Muthita Vanaporn The role of Burkholderia pseudomallei bprE gene in survival under stresses and infection
1:45–3:30 pm
VACCINE & PREVENTION
Invited Speakers
1:45 pm
Susie Dunachie, University of Oxford, Oxford, United Kingdom
Vaccines against melioidosis: How far are we?
2:15 pm
Ratanaporn Tangwangvivat, Department of Disease Control, Ministry of Public Health, Bangkok, Thailand
National plan for the prevention and control of melioidosis in Thailand
Selected Presentations
2:45 pm
David DeShazer, USAMRIID, Frederick, USA
3:00 pm
Christopher Cote, USAMRIID, Frederick, USA
Layered and integrated medical counter measures against Burkholderia pseudomallei infections in C57BL/6 mice
3:15 pm
Siobhán McClean, University College Dublin, Dublin, Ireland
Protective BpOmpW antigen stimulates the necessary immune correlates against melioidosis
3:30–4:00 pm
Break
4:00 pm
Concluding Remarks
Announcement of WMC 2024
